Methotrexate-related lymphoproliferative disorder arising in the gingiva of a patient with rheumatoid arthritis.

@article{Horie2015MethotrexaterelatedLD,
  title={Methotrexate-related lymphoproliferative disorder arising in the gingiva of a patient with rheumatoid arthritis.},
  author={Norio Horie and Ryutaro Kawano and Takahiro Kaneko and Tetsuo Shimoyama},
  journal={Australian dental journal},
  year={2015},
  volume={60 3},
  pages={408-11}
}
Methotrexate (MTX) is the primary drug used in the management of rheumatoid arthritis (RA) and other immune-mediated inflammatory diseases. MTX is a strong immunosuppressive agent and has been reported to cause iatrogenic immunodeficiency-associated lymphoproliferative disorders (LPDs). Stomatitis caused by MTX-related cytotoxicity may occur, but gingival… CONTINUE READING