Methotrexate-induced myelopathy mimicking subacute combined degeneration of the spinal cord.


Methotrexate (MTX), a folate antagonist, is widely used to treat hematological malignancies. Although it is known to cause myelopathy, little is known about the pathophysiology and natural history of this myelopathy. We describe a 42-year-old woman with acute lymphoblastic leukemia who was treated with chemotherapy consisting of intrathecal MTX who… (More)
DOI: 10.1016/j.jocn.2012.06.018

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