Methotrexate for multiple sclerosis.

  title={Methotrexate for multiple sclerosis.},
  author={O Peter Gray and Gavin V McDonnell and Raeburn B. Forbes},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Methotrexate is a potent immunosuppressant which in theory could reduce relapse rates and delay disease progression in multiple sclerosis (MS). Subsequently, clinical trials of methotrexate have been conducted in people with MS. OBJECTIVES To identify and summarise the evidence that methotrexate is beneficial and safe for people with MS. SEARCH STRATEGY We searched the Cochrane MS Group trials register (searched December 2003), the Cochrane Central Register of Controlled Trails… CONTINUE READING

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