Methotrexate compliance among patients with rheumatoid arthritis: the influence of disease activity, disease duration, and co-morbidity in a 10-year longitudinal study.

@article{Thurah2010MethotrexateCA,
  title={Methotrexate compliance among patients with rheumatoid arthritis: the influence of disease activity, disease duration, and co-morbidity in a 10-year longitudinal study.},
  author={Annette Ladefoged de Thurah and Mette N\orgaard and Martin Berg Johansen and Kristian Stengaard-Pedersen},
  journal={Scandinavian journal of rheumatology},
  year={2010},
  volume={39 3},
  pages={197-205}
}
OBJECTIVE To assess methotrexate (MTX) compliance among rheumatoid arthritis (RA) patients. METHODS Using prescription data, we conducted a 10-year longitudinal study among RA patients who were first-time MTX users. MTX compliance was expressed as the continuous measure of medication gaps (CMG), that is the proportion of treatment gaps compared with the total observation period stratified by age, sex, C-reactive protein (CRP), haemoglobin, co-morbidity, concurrent medication, and disease… CONTINUE READING
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