Methods to analyse cost data of patients who withdraw in a clinical trial setting

@article{Oostenbrink2003MethodsTA,
  title={Methods to analyse cost data of patients who withdraw in a clinical trial setting},
  author={Jan B. Oostenbrink and Maiwenn J. Al and Maureen P.M.H. Rutten-van M{\"o}lken},
  journal={PharmacoEconomics},
  year={2003},
  volume={21},
  pages={1103-1112}
}
AbstractBackground: Missing data resulting from premature study withdrawal are a common problem in the analysis of longitudinal data in clinical trials. To date, this subject has received little attention in the context of economic evaluations and with regard to the analysis of cost data. Objectives: To (i) demonstrate the impact of patients who drop out during the study on the outcomes of an economic evaluation, and (ii) to compare the mean and variation in costs after applying five different… CONTINUE READING

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