Methods for studying mutagenesis and checkpoints in Schizosaccharomyces pombe.

Abstract

Mutations in genome caretaker genes can induce genomic instability, which are potentially early events in tumorigenesis. Cells have evolved biological processes to cope with the genomic insults. One is a multifaceted response, termed checkpoint, which is a network of signaling pathways to coordinate cell cycle transition with DNA repair, activation of… (More)

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Cite this paper

@article{Kai2006MethodsFS, title={Methods for studying mutagenesis and checkpoints in Schizosaccharomyces pombe.}, author={Mihoko Kai and Lorena Taricani and Teresa S-F Wang}, journal={Methods in enzymology}, year={2006}, volume={409}, pages={183-94} }