Methods for quantifying adipose tissue insulin resistance in overweight/obese humans

@article{Horst2017MethodsFQ,
  title={Methods for quantifying adipose tissue insulin resistance in overweight/obese humans},
  author={Kasper W. ter Horst and Katherine Galen and Pim W. Gilijamse and Annick V Hartstra and Pieter F. de Groot and Fleur M. van der Valk and Mariette T Ackermans and Max Nieuwdorp and Johannes Anthonius Romijn and Mireille J Serlie},
  journal={International Journal of Obesity},
  year={2017},
  volume={41},
  pages={1288-1294}
}
Background/Objectives:Insulin resistance of adipose tissue is an important feature of obesity-related metabolic disease. However, assessment of lipolysis in humans requires labor-intensive and expensive methods, and there is limited validation of simplified measurement methods. We aimed to validate simplified methods for the quantification of adipose tissue insulin resistance against the assessment of insulin sensitivity of lipolysis suppression during hyperinsulinemic–euglycemic clamp studies… CONTINUE READING
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