Methods for prediction of peptide binding to MHC molecules: a comparative study.

@article{Yu2002MethodsFP,
  title={Methods for prediction of peptide binding to MHC molecules: a comparative study.},
  author={Kun Yu and Nikolai Petrovsky and Christian Sch{\"o}nbach and Judice L. Y. Koh and Vladimir Brusic},
  journal={Molecular medicine},
  year={2002},
  volume={8 3},
  pages={
          137-48
        }
}
BACKGROUND A variety of methods for prediction of peptide binding to major histocompatibility complex (MHC) have been proposed. These methods are based on binding motifs, binding matrices, hidden Markov models (HMM), or artificial neural networks (ANN). There has been little prior work on the comparative analysis of these methods. MATERIALS AND METHODS We performed a comparison of the performance of six methods applied to the prediction of two human MHC class I molecules, including binding… CONTINUE READING

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