Methods for multiple-marker mapping of quantitative trait loci in half-sib populations

@article{Knott1996MethodsFM,
  title={Methods for multiple-marker mapping of quantitative trait loci in half-sib populations},
  author={Sara A. Knott and J. M. Elsen and Chris S. Haley},
  journal={Theoretical and Applied Genetics},
  year={1996},
  volume={93},
  pages={71-80}
}
In this paper we consider the detection of individual loci controlling quantitative traits of interest (quantitative trait loci or QTLs) in the large half-sib family structure found in some species. Two simple approaches using multiple markers are proposed, one using least squares and the other maximum likelihood. These methods are intended to provide a relatively fast screening of the entire genome to pinpoint regions of interest for further investigation. They are compared with a more… CONTINUE READING
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Genetics 121.185-199 NIEMANN-S0RENSON, A. and ROBERTSON, A

S. A. KNOTT, C. S. HALEY
Acta Agric. Scand • 1992