Methods for multiple-marker mapping of quantitative trait loci in half-sib populations

  title={Methods for multiple-marker mapping of quantitative trait loci in half-sib populations},
  author={S. Knott and J. Elsen and C. Haley},
  journal={Theoretical and Applied Genetics},
  • S. Knott, J. Elsen, C. Haley
  • Published 2004
  • Biology, Medicine
  • Theoretical and Applied Genetics
  • In this paper we consider the detection of individual loci controlling quantitative traits of interest (quantitative trait loci or QTLs) in the large half-sib family structure found in some species. Two simple approaches using multiple markers are proposed, one using least squares and the other maximum likelihood. These methods are intended to provide a relatively fast screening of the entire genome to pinpoint regions of interest for further investigation. They are compared with a more… CONTINUE READING

    Tables and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    QTL Express: mapping quantitative trait loci in simple and complex pedigrees
    • 518
    • Open Access
    Multitrait least squares for quantitative trait loci detection.
    • 230
    • Open Access
    Detection of quantitative trait loci for backfat thickness and intramuscular fat content in pigs (Sus scrofa).
    • 321
    • Open Access
    Detection of genes influencing economic traits in three French dairy cattle breeds
    • 257
    • Open Access
    Mapping quantitative trait loci in complex pedigrees: a two-step variance component approach.
    • 165
    • Open Access


    Publications referenced by this paper.
    Empirical threshold values for quantitative trait mapping.
    • 4,708
    • Open Access
    Introduction to Quantitative Genetics.
    • 13,431
    Interval mapping of multiple quantitative trait loci.
    • 856
    • Open Access
    Mapping quantitative trait loci in crosses between outbred lines using least squares.
    • 707