Methods for measuring glycogen cycling.

  title={Methods for measuring glycogen cycling.},
  author={Bernard R. Landau},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={281 3},
  • Bernard R. Landau
  • Published 2001 in
    American journal of physiology. Endocrinology and…
Simultaneous synthesis and breakdown of glycogen is called glycogen cycling. The extent of hyperglycemia and decreased glycogen stores in diabetes mellitus may relate in part to the extent cycling occurs. Four methods have been introduced to estimate its extent in liver in humans. 1) In the fasted state, the rate of net hepatic glycogenolysis, i.e., glycogen breakdown minus synthesis, is estimated using NMR, and the rate of glycogenolysis is estimated from deuterium labeling of blood glucose on… CONTINUE READING


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