Methods for homocysteine analysis and biological relevance of the results.

@article{Ducros2002MethodsFH,
  title={Methods for homocysteine analysis and biological relevance of the results.},
  author={V{\'e}ronique Ducros and Karine Demuth and M P Sauvant and Muriel Muraine Quillard and Elisabeth Causs{\'e} and Mirande Candito and M H Read and Jocelyne Drai and Isabelle Garcia and Marie-Françoise Gerhardt},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2002},
  volume={781 1-2},
  pages={207-26}
}
It is now widely accepted that increased total plasma homocysteine (tHcy) is a risk factor for cardiovascular disease. Hyperhomocysteinemia can be caused by impaired enzyme function as a result of genetic mutation or vitamin B (B(2), B(6), B(9), B(12)) deficiency. A lot of methods are now available for tHcy determination. High-pressure liquid chromatography (HPLC) with fluorescence detection are at present the most widely used methods but immunoassays, easier to use, begin to supplant in-house… CONTINUE READING

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