Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations.

@article{Tarpey2004MethodsFD,
  title={Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations.},
  author={Margaret M. Tarpey and David A Wink and Matthew B Grisham},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={286 3},
  pages={
          R431-44
        }
}
Facile detection of reactive oxygen and nitrogen species in biologic systems is often problematic. This is a result of the numerous cellular mechanisms, both enzymatic and nonenzymatic involved in their catabolism/decomposition, the complex and overlapping nature of their reactivities, as well as the often limited intracellular access of detector systems. This review describes approaches to the direct and indirect measurement of different reactive metabolites of oxygen and nitrogen. Particular… CONTINUE READING

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SHOWING 1-10 OF 150 REFERENCES

Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.

  • The Journal of biological chemistry
  • 1994
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Cytochrome c. In: Handbook of Methods for Oxygen Radical Research, edited by Greenwald RA

I. Fridovich
  • Boca Raton, FL: CRC,
  • 1985
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL