Methods for detection of hemoglobin variants and hemoglobinopathies in the routine clinical laboratory.

@article{Schneider1978MethodsFD,
  title={Methods for detection of hemoglobin variants and hemoglobinopathies in the routine clinical laboratory.},
  author={Rose G. Schneider},
  journal={CRC critical reviews in clinical laboratory sciences},
  year={1978},
  volume={9 3},
  pages={243-71}
}
Many mutant hemoglobins and hemoglobinopathies can be identified with a high degree of specificity in the routine clinical laboratory. The most frequent abnormalities--those involving Hb S or C--are usually easily detectable in small amounts of sample analyzed by two simple methods of electrophoresis: cellulose acetate at pH 8.5 and citrate agar at pH 6… CONTINUE READING