Methods for clinical assessment of insulin sensitivity and beta-cell function.

@article{Pacini2003MethodsFC,
  title={Methods for clinical assessment of insulin sensitivity and beta-cell function.},
  author={Giovanni Pacini and Andrea Mari},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  year={2003},
  volume={17 3},
  pages={305-22}
}
The quantitative assessment of insulin sensitivity (IS) and beta-cell function (BCF) is fundamental in the study of metabolic disorders. The most relevant experimental tests and data analysis methods for assessing both IS and BCF are described and their characteristic features discussed. Advantages and limitations of each method are comparatively reviewed to help investigators choose the most suitable test for their needs. The problem of properly relating BCF to IS is also addressed. Particular… CONTINUE READING