Methods for Studying and Structure–Function Relationships of Non-Fibrillar Protein Assemblies in Alzheimer's Disease and Related Disorders

@inproceedings{Bitan2014MethodsFS,
  title={Methods for Studying and Structure–Function Relationships of Non-Fibrillar Protein Assemblies in Alzheimer's Disease and Related Disorders},
  author={Farid Rahimi and Gal Bitan},
  year={2014}
}
Several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and prion diseases, are characterized by intra- and/or extracellular deposition of fibrillar proteinaceous aggregates, and by extensive, neuron loss. Related non-neuropathic systemic diseases, e.g., light-chain and senile systemic amyloidoses, and other organ-specific diseases, such as dialysis-related amyloidosis and type-2 diabetes, also are characterized by deposition of aggregated proteins. It is debated… CONTINUE READING

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