Methods for 17β-oestradiol administration to rats.

@article{Isaksson2011MethodsF1,
  title={Methods for 17β-oestradiol administration to rats.},
  author={Ida-Maria Isaksson and Annette Theodorsson and Elvar Theodorsson and Jakob O. Strom},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={2011},
  volume={71 7},
  pages={583-92}
}
Several studies indicate that the beneficial or harmful effects of oestrogens in stroke are dose-dependent. Rats are amongst the most frequently used animals in these studies, which calls for thoroughly validated methods for administering 17β-oestradiol to rats. In an earlier study we characterised three different administration methods for 17β-oestradiol over 42 days. The present study assesses the concentrations in a short time perspective, with the addition of a novel peroral method. Female… CONTINUE READING
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