Methods employed for induction and analysis of experimental myocardial infarction in mice.

@article{Borst2011MethodsEF,
  title={Methods employed for induction and analysis of experimental myocardial infarction in mice.},
  author={Oliver Borst and Carmen Ochmann and Tanja Schoenberger and Christoph Jacoby and Konstantinos Stellos and Peter Seizer and Ulrich Fl{\"o}gel and Florian Lang and Meinrad Gawaz},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2011},
  volume={28 1},
  pages={1-12}
}
Myocardial ischemia und subsequent reperfusion is followed by a complex sequence of pathophysiological responses involving inflammatory cell infiltration and cytokine release as well as postinfarction wound healing and myocardial tissue remodeling. With the development of gene targeted mice the contribution of individual gene products to the pathophysiology of myocardial ischemia and reperfusion can be defined leading to an increasing interest in the widely-used mouse model of myocardial… CONTINUE READING

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