Methods and rationale for derivation of a reference dose for methylmercury by the U.S. EPA.

  title={Methods and rationale for derivation of a reference dose for methylmercury by the U.S. EPA.},
  author={Deborah C. Rice and Rita S Schoeny and Kate Mahaffey},
  journal={Risk analysis : an official publication of the Society for Risk Analysis},
  volume={23 1},
In 2001, the U.S. Environmental Protection Agency derived a reference dose (RfD) for methylmercury, which is a daily intake that is likely to be without appreciable risk of deleterious effects during a lifetime. This derivation used a series of benchmark dose (BMD) analyses provided by a National Research Council (NRC) panel convened to assess the health effects of methylmercury. Analyses were performed for a number of endpoints from three large longitudinal cohort studies of the… CONTINUE READING
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