Methods and matrices: approaches to identifying miRNAs for Nasopharyngeal carcinoma

  title={Methods and matrices: approaches to identifying miRNAs for Nasopharyngeal carcinoma},
  author={Jordan L. Plieskatt and Gabriel Rinaldi and Yanjung Feng and Paul H. Levine and Samantha E. Easley and Elizabeth Ferreira Martinez and Salman Hashmi and Nader Sadeghi and Paul J. Brindley and Jeffrey Michael Bethony and Jason P. Mulvenna},
  booktitle={Journal of Translational Medicine},
Nasopharyngeal carcinoma (NPC) is a solid tumor of the head and neck. Multimodal therapy is highly effective when NPC is detected early. However, due to the location of the tumor and the absence of clinical signs, early detection is difficult, making a biomarker for the early detection of NPC a priority. The dysregulation of small non-coding RNAs (miRNAs) during carcinogenesis is the focus of much current biomarker research. Herein, we examine several miRNA discovery methods using two sample… CONTINUE READING
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