Methodology for profiling the steroid metabolome in animal tissues using ultraperformance liquid chromatography-electrospray-time-of-flight mass spectrometry.

@article{FloresValverde2008MethodologyFP,
  title={Methodology for profiling the steroid metabolome in animal tissues using ultraperformance liquid chromatography-electrospray-time-of-flight mass spectrometry.},
  author={Anel M Flores-Valverde and Elizabeth M Hill},
  journal={Analytical chemistry},
  year={2008},
  volume={80 22},
  pages={8771-9}
}
The advent of mass spectrometry-based metabolite profiling techniques should allow investigations into the behavior and regulation of many of the low abundant signaling molecules present in the animal metabolome such as hormones and so aid investigations into the mechanisms of endocrine system function and disorders. Examples of their potential applications include endocrine-related diseases such as some cancers, as well as endocrine disruption in wildlife and humans caused by some… CONTINUE READING