Methodological issues in outcome studies of at-risk infants.

  title={Methodological issues in outcome studies of at-risk infants.},
  author={Glen P. Aylward},
  journal={Journal of pediatric psychology},
  volume={27 1},
OBJECTIVE To identify methodologic problems found in follow-up studies of infants at biologic and environmental risk and provide solutions and recommendations. METHODS This article is a literature review. RESULTS Problems fall into four groupings: (1) conceptualization/design issues, 2) subject population concerns, 3) procedural issues, and 4) measurement/outcome concerns. CONCLUSIONS Main-effect models are not useful; confounding and mediating variables must be identified. In addition… CONTINUE READING