Methodological issues in microdialysis sampling for pharmacokinetic studies.

Abstract

Microdialysis is an in vivo technique that permits monitoring of local concentrations of drugs and metabolites at specific sites in the body. Microdialysis has several characteristics, which makes it an attractive tool for pharmacokinetic research. About a decade ago the microdialysis technique entered the field of pharmacokinetic research, in the brain… (More)

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Cite this paper

@article{Lange2000MethodologicalII, title={Methodological issues in microdialysis sampling for pharmacokinetic studies.}, author={E C M de Lange and Albertus Gerrit de Boer and D. D. Breimer}, journal={Advanced drug delivery reviews}, year={2000}, volume={45 2-3}, pages={125-48} }