• Chemistry
  • Published 2016

Method for promoting efficiency of purification of fc region-containing polypeptide

@inproceedings{2016MethodFP,
  title={Method for promoting efficiency of purification of fc region-containing polypeptide},
  author={田中 信幸 and 百瀬 瑠美子},
  year={2016}
}
It is found that, when an Fc region in which a first polypeptide chain thereof can bind to a protein A resin but a second polypeptide chain thereof cannot bind to the resin or can bind to the resin weakly is employed as the Fc region in an Fc region-containing polypeptide, the bonding amount of the Fc region-containing polypeptide per unit volume of the resin can be increased and the Fc region-containing polypeptide can be purified with higher efficiency.