• Corpus ID: 102959683

Method for detecting and analyzing arranon

  title={Method for detecting and analyzing arranon},
  author={姜威 and 孙学伟 and 孙德杰 and 米长江 and 顾群},
The invention discloses a method for detecting and analyzing arranon. The method comprises a high-efficiency liquid chromatography of the arranon and arranon injection solution and is characterized by comprising the following steps of: detecting and analyzing related substances such as 2-amino-6-methoxy purine, arranon optical isomers, arranon geometric isomers and the like in the arranon and the arranon injection solution by using water, phosphoric acid and acetonitrile as mobile phases by a… 


Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates
The excellent CSF penetration of nelarabine and ara-G supports further study of the contribution of nerabine to the prevention and treatment of CNS leukemia.
Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells.
  • V. Gandhi, W. Plunkett, M. Keating
  • Medicine, Biology
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2001
Clinical responses suggest the need for further exploration of nelarabine against fludarabines-refractory diseases, and determination of ara-GTP levels in the target tumor population may provide a prognostic test for the activity of nesbittsylguanine.