Method development and Method validation for the simultaneous estimation of Metformin HCL and Linagliptin in Bulk and tablet Dosage Form by RP-HPLC Method

@inproceedings{Swamy2013MethodDA,
  title={Method development and Method validation for the simultaneous estimation of Metformin HCL and Linagliptin in Bulk and tablet Dosage Form by RP-HPLC Method},
  author={A. Janardhan Swamy and K Baba},
  year={2013}
}
A rapid, highly sensitive, economical and accurate RP-HPLC method was developed for simultaneous estimation of Metformin HCL and Linagliptin in Bulk and Pharmaceutical Dosage form. The separation was achieved by Hypersil C18 column (250 × 4.6 mm, 5 μ particle size) with mobile phase consisting of phosphate buffer (pH 5.6, diluted with orthophosphoric acid), methanol and acetonitrile in the ratio of 40:5:55 v/v, using flow rate 1.0 mL/min and eluents monitored at 233nm .The developed method was… CONTINUE READING

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