Methionine intolerance: a possible risk factor for coronary artery disease.

  title={Methionine intolerance: a possible risk factor for coronary artery disease.},
  author={D R Murphy-Chutorian and M P Wexman and Anthony J. Grieco and J A Heininger and Edward Glassman and Gerald E. Gaull and Salina K.F. Ng and Frederick Feit and K Wexman and A C Fox},
  journal={Journal of the American College of Cardiology},
  volume={6 4},
Homocystinuria, an inherited disorder associated with premature atherosclerosis, represents a severe form of methionine intolerance. To analyze the importance of milder forms of methionine intolerance in the genesis of vascular disease, the relation between provokable methionine intolerance and coronary artery disease was investigated. In a group of 138 men, aged 31 to 65 years (mean 53), referred for cardiac catheterization, plasma homocystine was measured before and 6 hours after an oral l… CONTINUE READING
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