Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein.


Protein methylation pathways comprise methionine adenosyltransferase (MAT), which produces S-adenosylmethionine (SAM) and SAM-dependent substrate-specific methyltransferases. However, the function of MAT in the nucleus is largely unknown. MafK represses or activates expression of heme oxygenase-1 (HO-1) gene, depending on its heterodimer partners… (More)
DOI: 10.1016/j.molcel.2011.02.018


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