Methimazole-induced agranulocytosis: growth inhibition of myeloid progenitor cells by the patient's serum.

Abstract

The mechanism for agranulocytosis induced by antithyroid drugs is not established. The few available studies have proposed an immune-mediated process against mature granulocytes. We investigated the effect of methimazole and propylthiouracil and serum from a patient with methimazole-induced agranulocytosis on marrow myeloid colony growth. In the presence of… (More)

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Cite this paper

@article{Douer1988MethimazoleinducedAG, title={Methimazole-induced agranulocytosis: growth inhibition of myeloid progenitor cells by the patient's serum.}, author={Dan Douer and Zemach Eisenstein}, journal={European journal of haematology}, year={1988}, volume={40 1}, pages={91-4} }