Methemoglobin—It's not just blue: A concise review

@article{Umbreit2007MethemoglobinItsNJ,
  title={Methemoglobin—It's not just blue: A concise review},
  author={J. Umbreit},
  journal={American Journal of Hematology},
  year={2007},
  volume={82}
}
  • J. Umbreit
  • Published 2007
  • Chemistry, Medicine
  • American Journal of Hematology
  • Hemoglobin has functions besides carrying oxygen to the tissues, and regulates vascular tone and inflammation via a redox couple with methemoglobin. Hemoglobin has iron in the reduced valance Fe(II) and methemoglobin has iron in the oxidized valance Fe (III), with a free energy capable of producing water from oxygen. In generating methemoglobin the couple functions as a nitrite reductase. The degree of oxidation of hemoglobin senses the oxygen level in the blood and uses its ability to produce… CONTINUE READING
    273 Citations

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