Methamphetamine toxicity and messengers of death

  title={Methamphetamine toxicity and messengers of death},
  author={Irina N. Krasnova and Jean Lud Cadet},
  journal={Brain Research Reviews},
Methamphetamine (METH) is an illicit psychostimulant that is widely abused in the world. Several lines of evidence suggest that chronic METH abuse leads to neurodegenerative changes in the human brain. These include damage to dopamine and serotonin axons, loss of gray matter accompanied by hypertrophy of the white matter and microgliosis in different brain areas. In the present review, we summarize data on the animal models of METH neurotoxicity which include degeneration of monoaminergic… CONTINUE READING
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