Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes

@inproceedings{Cao2016MethamphetaminePH,
  title={Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes},
  author={Lu Cao and Mingui Fu and Santosh Kumar and Anil Kumar},
  booktitle={Cell Death and Disease},
  year={2016}
}
Methamphetamine (METH), a commonly used controlled substance, is known to exacerbate neuropathological dysfunction in HIV-infected individuals. The neuropathological manifestation results from cell death or dysfunction in the central nervous system (CNS) wherein autophagy is expected to have an important role. Autophagy is generally considered protective… CONTINUE READING