Methamphetamine induces trace amine-associated receptor 1 (TAAR1) expression in human T lymphocytes: role in immunomodulation.

@article{Sriram2016MethamphetamineIT,
  title={Methamphetamine induces trace amine-associated receptor 1 (TAAR1) expression in human T lymphocytes: role in immunomodulation.},
  author={Uma Sriram and Jonathan M. Cenna and Bijayesh Haldar and Nicole C. Fernandes and Roshanak Razmpour and Shongshan Fan and Servio H. Ramirez and Raghava Potula},
  journal={Journal of leukocyte biology},
  year={2016},
  volume={99 1},
  pages={213-23}
}
The novel transmembrane G protein-coupled receptor, trace amine-associated receptor 1 (TAAR1), represents a potential, direct target for drugs of abuse and monoaminergic compounds, including amphetamines. For the first time, our studies have illustrated that there is an induction of TAAR1 mRNA expression in resting T lymphocytes in response to methamphetamine. Methamphetamine treatment for 6 h significantly increased TAAR1 mRNA expression (P < 0.001) and protein expression (P < 0.01) at 24 h… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Similar Papers

Loading similar papers…