Methamphetamine induces DNA damage in specific regions of the female rat brain

@article{Johnson2015MethamphetamineID,
  title={Methamphetamine induces DNA damage in specific regions of the female rat brain},
  author={Zane Johnson and Jace Venters and Fay A. Guarraci and Maha Zewail-Foote},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={2015},
  volume={42}
}
Methamphetamine (METH) is a highly addictive psychostimulant that has been shown to produce neurotoxicity. Methamphetamine increases the release of dopamine by reversing the direction of monoamine transporter proteins, leading to the formation of reactive oxygen species in the brain. In this study, we examined the effect of METH on DNA damage in vivo using the single cell gel electrophoresis assay (comet assay) under two different conditions. Rats treated with multiple doses of METH (10 mg/kg… 

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