Methamphetamine-induced sensitization includes a functional upregulation of ventral pallidal 5-HT2A/2C receptors.

@article{Napier2008MethamphetamineinducedSI,
  title={Methamphetamine-induced sensitization includes a functional upregulation of ventral pallidal 5-HT2A/2C receptors.},
  author={T. Celeste Napier and Erik D Istre},
  journal={Synapse},
  year={2008},
  volume={62 1},
  pages={14-21}
}
Methamphetamine (METH) causes the release of serotonin (5-HT), but little is known about how repeated exposure to METH modifies serotonergic receptor function, especially in the ventral pallidum (VP), a brain region highly innervated by serotonin inputs. The current study was designed to ascertain if ventral pallidal neurons are functionally upregulated 3 days after a behaviorally sensitizing treatment regimen of METH, and whether these effects could be revealed by activating the 5-HT2A/2C… CONTINUE READING