Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review

@article{Cadet2005MethamphetamineinducedNA,
  title={Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review},
  author={Jean Lud Cadet and Subramaniam Jayanthi and Xiaolin Deng},
  journal={Neurotoxicity Research},
  year={2005},
  volume={8},
  pages={199-206}
}
The abuse of the illicit drug methamphetamine (METH) is a major concern because it can cause terminal degeneration and neuronal cell death in the brain. METH-induced cell death occurs via processes that resemble apoptosis. In the present review, we discuss the role of various apoptotic events in the causation of METH-induced neuronal apoptosisin vitro andin vivo. Studies using comprehensive approaches to gene expression profiling have allowed for the identification of several genes that are up… CONTINUE READING
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