Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge

Abstract

Methamphetamine induces neurotransmitter reductions and neurotoxicity at high doses in adult animals, but its effects on early brain development and behavior have received little attention. In this experiment the effects of methamphetamine exposure during a period equivalent to the human third trimester were examined. Rats (Sprague-Dawley CD) were injected… (More)
DOI: 10.1007/BF02249329

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