Methamphetamine enhances cell-associated feline immunodeficiency virus replication in astrocytes

  title={Methamphetamine enhances cell-associated feline immunodeficiency virus replication in astrocytes},
  author={Mikhail A Gavrilin and Lawrence E. Mathes and Michael D Podell},
  journal={Journal of NeuroVirology},
Human immunodeficiency virus (HIV) infection among substance abusers is on the rise worldwide. Psychostimulants, and in particular methamphetamine (METH), have detrimental effects on the immune system as well as causing a progressive neurodegeneration, similar to HIV infection. Many Lentivirinae, including feline immunodeficiency virus (FIV), penetrate into the central nervous system early in the course of infection with astrocytes serving as a reservoir of chronic brain infection. We… CONTINUE READING


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