Methadone, Buprenorphine, and Naltrexone for the Treatment of Opioid Use Disorder in Pregnant Women

  title={Methadone, Buprenorphine, and Naltrexone for the Treatment of Opioid Use Disorder in Pregnant Women},
  author={Tran H. Tran and Brooke L. Griffin and R. H. Stone and Kathleen M. Vest and Timothy J. Todd},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  • Tran H. Tran, Brooke L. Griffin, +2 authors Timothy J. Todd
  • Published 2017
  • Medicine
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • Pregnant women with opioid use disorder can be treated with methadone, buprenorphine, or naltrexone to reduce opioid use and improve retention to treatment. In this review, we compare the pregnancy outcomes of methadone, buprenorphine, and naltrexone in clinical trials and discuss the potential behavioral and developmental effects of these agents seen in offspring in animal studies. Important clinical considerations in the management of opioid use disorder in pregnant women and their infants… CONTINUE READING
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