Methacholine and ovalbumin challenges assessed by forced oscillations and synchrotron lung imaging.

@article{Bayat2009MethacholineAO,
  title={Methacholine and ovalbumin challenges assessed by forced oscillations and synchrotron lung imaging.},
  author={S Bayat and Satu Strengell and Liisa Porra and Tibor Janosi and Ferenc Pet{\'a}k and Heikki Suhonen and Pekka Suortti and Zolt{\'a}n Hantos and Anssi R. A. Sovij{\"a}rvi and Walid Habre},
  journal={American journal of respiratory and critical care medicine},
  year={2009},
  volume={180 4},
  pages={296-303}
}
RATIONALE Methacholine (Mch) is routinely used to assess bronchial hyperreactivity; however, little is known about the differences in the lung response pattern between this provocation and that observed with ovalbumin (Ova) after allergic sensitization. OBJECTIVES To compare (1) the central versus peripheral effects of Mch and Ova within the lung by combining measurements of airway and tissue mechanics with synchrotron radiation (SR) imaging, and (2) to assess the extent to which mechanical… CONTINUE READING