Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30.

Abstract

We studied 31 nondiabetic, habitually (> or =5 years) morbidly obese subjects (mean +/- SD body mass index [BMI] 43 +/- 8.7, median 43). Our specific aim was to determine whether metformin (2.55 g/d for 28 weeks) would ameliorate morbid obesity and reduce centripetal obesity; lipid and lipoprotein cholesterol, insulin, and leptin levels; and plasminogen… (More)

Topics

Cite this paper

@article{Glck2001MetforminRW, title={Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30.}, author={Claudia Gl{\"u}ck and Rex0301jean Fontaine and P. Wang and Madhuri Subbiah and Konrad Weber and E Illig and Patricia Streicher and Luann Sieve-Smith and Tara Tracy and Jason E. Lang and Peter A. McCullough}, journal={Metabolism: clinical and experimental}, year={2001}, volume={50 7}, pages={856-61} }