Metformin reduces all-cause mortality and diseases of ageing independent of its effect on diabetes control: A systematic review and meta-analysis

@article{Campbell2017MetforminRA,
  title={Metformin reduces all-cause mortality and diseases of ageing independent of its effect on diabetes control: A systematic review and meta-analysis},
  author={Jared M. Campbell and Susan M. Bellman and M. Stephenson and K. Lisy},
  journal={Ageing Research Reviews},
  year={2017},
  volume={40},
  pages={31-44}
}
This systematic review investigated whether the insulin sensitiser metformin has a geroprotective effect in humans. Pubmed and Embase were searched along with databases of unpublished studies. Eligible research investigated the effect of metformin on all-cause mortality or diseases of ageing relative to non-diabetic populations or diabetics receiving other therapies with adjustment for disease control achieved. Overall, 260 full-texts were reviewed and 53 met the inclusion criteria. Diabetics… Expand
Association of metformin monotherapy or combined therapy with cardiovascular risks in patients with type 2 diabetes mellitus
Mechanisms of action of metformin with special reference to cardiovascular protection
Mortality Associated with Metformin Versus Sulfonylurea Initiation: A Cohort Study of Veterans with Diabetes and Chronic Kidney Disease
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 105 REFERENCES
The impact of metformin use on survival in kidney cancer patients with diabetes: a meta-analysis
Metformin Improves Overall Survival of Colorectal Cancer Patients with Diabetes: A Meta-Analysis
Effect of Metformin-Containing Antidiabetic Regimens on All-cause Mortality in Veterans With Type 2 Diabetes Mellitus
The effect of metformin on the incidence of type 2 diabetes mellitus and cardiovascular disease risk factors in overweight and obese subjects--the Carmos study.
  • E. Andreadis, P. Katsanou, +4 authors E. Diamantopoulos
  • Medicine
  • Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • 2009
14-Year Risk of All-Cause Mortality According to Hypoglycaemic Drug Exposure in a General Population
Metformin Use Is Associated with Reduced Incidence and Improved Survival of Endometrial Cancer: A Meta-Analysis
Long-term metformin usage and cognitive function among older adults with diabetes.
Metformin does not alter the risk of lung cancer: a case-control analysis.
...
1
2
3
4
5
...