Metformin in the treatment of clomiphene citrate-resistant women with polycystic ovary syndrome undergoing in vitro fertilisation treatment: a randomised controlled trial.

@article{Qublan2009MetforminIT,
  title={Metformin in the treatment of clomiphene citrate-resistant women with polycystic ovary syndrome undergoing in vitro fertilisation treatment: a randomised controlled trial.},
  author={Hussein S. Qublan and S Al-Khaderei and A N Abu-Salem and A Al-Zpoon and Mohammed Jamal Al-khateeb and NS Al-ibrahim and Mohamad Megdadi and N Al-Ahmad},
  journal={Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology},
  year={2009},
  volume={29 7},
  pages={651-5}
}
This study was conducted to determine the efficacy of metformin vs placebo in women with polycystic ovary syndrome (PCOS) undergoing IVF treatment. A total of 66 CC-resistant patients were studied prospectively. The women were randomly assigned to receive 850 mg of metformin (n = 34) or placebo (n = 32) twice daily that started 1 month before commencing the IVF treatment and continued to the day of the pregnancy test. Compared with the metformin-treated group, women who received a placebo had a… CONTINUE READING