Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses.

@article{Harborne2005MetforminAW,
  title={Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses.},
  author={Lyndal R Harborne and Naveed 4 Sattar and Jane E Norman and Richard Fleming},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 8},
  pages={4593-8}
}
CONTEXT Metformin treatment of women with polycystic ovary syndrome (PCOS) is widespread, as determined by studies with diverse patient populations. No comparative examination of weight changes or metabolite responses to different doses has been reported. OBJECTIVE The aim of this study was to determine whether different doses of metformin (1500 or 2550 mg/d) would have different effects on body weight, circulating hormones, markers of inflammation, and lipid profiles. DESIGN The study… CONTINUE READING

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