Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment.

@article{Silva1979MetforminAC,
  title={Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment.},
  author={S R de Silva and David John Betteridge and J E Shawe and Andrew G. Cudworth and K. George M. M. Alberti},
  journal={Diabete & metabolisme},
  year={1979},
  volume={5 3},
  pages={223-9}
}
Blood glucose, lipoproteins, non-esterified fatty acids, fibrinogen and intermediary metabolites were measured in twenty-two diet failed maturity onset diabetics during a double blind crossover study of metformin (1.7 g/day) or clofibrate (2 g/day) therapy. Patients received combined therapy for a final two month period. Four patients had 12 hour metabolic… CONTINUE READING