Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

  title={Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review},
  author={Monica Franciosi and Giuseppe Lucisano and Emanuela Lapice and Giovanni F M Strippoli and Fabio Pellegrini and Antonio Nicolucci},
  booktitle={PloS one},
AIMS/HYPOTHESIS Diabetes treatments were related with either an increased or reduced risk of cancer. There is ongoing debate about a potential protective action of metformin. To summarize evidence on the association between metformin and risk of cancer and cancer mortality in patients with diabetes. METHODS DATA SOURCE MEDLINE and EMBASE (January 1966-April 2012). We selected randomized studies comparing metformin and other hypoglycaemic agents and observational studies exploring the… CONTINUE READING
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