Metformin Induces Ultrastructural Alterations in Hepatocytes of Spontaneously Hypertensive Rats

  • Hepatocitos de Ratas Espontáneamente Hipertensas Rajendra Gharbaran
  • Published 2014

Abstract

Metformin, an oral biguanide approved for the treatment of type II diabetes is widely prescribed for other clinical conditions. Currently, metformin is being investigated as potential anti-tumor agent. However, there have been recent concerns about hepatotoxicity associated with the use of metformin. This study, by means of high resolution transmission… (More)

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