Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes

  title={Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes},
  author={Gijs W D Landman and Nanne Kleefstra and Kornelis J. J. van Hateren and Klaas H Groenier and Rijk O. B. Gans and Henk J G Bilo},
  booktitle={Diabetes care},
OBJECTIVE Several studies have suggested an association between specific diabetes treatment and cancer mortality. We studied the association between metformin use and cancer mortality in a prospectively followed cohort. RESEARCH DESIGN AND METHODS In 1998 and 1999, 1,353 patients with type 2 diabetes were enrolled in the Zwolle Outpatient Diabetes project Integrating Available Care (ZODIAC) study in the Netherlands. Vital status was assessed in January 2009. Cancer mortality rate was… CONTINUE READING
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Publications referenced by this paper.
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Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2009
View 1 Excerpt

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I BenSahra, K Laurent, +6 authors F Bost
Oncogene • 2008

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