Metformin: taking away the candy for cancer?

  title={Metformin: taking away the candy for cancer?},
  author={Mathilde Jalving and Jourik A. Gietema and Joop Daniel Lefrandt and Steven de Jong and Anna K. L. Reyners and Rijk O. B. Gans and Elisabeth GE de Vries},
  journal={European journal of cancer},
  volume={46 13},
Metformin is widely used in the treatment of diabetes mellitus type 2 where it reduces insulin resistance and diabetes-related morbidity and mortality. Population-based studies show that metformin treatment is associated with a dose-dependent reduction in cancer risk. The metformin treatment also increases complete pathological tumour response rates following neoadjuvant chemotherapy for breast cancer, suggesting a potential role as an anti-cancer drug. Diabetes mellitus type 2 is associated… CONTINUE READING
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