Metformin: its botanical background

  title={Metformin: its botanical background},
  author={C. J. Bailey and Caroline Day},
  journal={Practical Diabetes International},
  • C. J. BaileyC. Day
  • Published 1 April 2004
  • Chemistry, Medicine
  • Practical Diabetes International
This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat’s rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957. Copyright © 2004 John Wiley & Sons, Ltd. Practical Diabetes Int 2004; 21(3): 115–117 

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