Metformin: Effects on Micro and Macrovascular Complications in Type 2 Diabetes

@article{Bailey2008MetforminEO,
  title={Metformin: Effects on Micro and Macrovascular Complications in Type 2 Diabetes},
  author={Clifford J Bailey},
  journal={Cardiovascular Drugs and Therapy},
  year={2008},
  volume={22},
  pages={215-224}
}
The antihyperglycaemic agent metformin is widely used in the treatment of type 2 diabetes. Data from the UK Prospective Diabetes Study and retrospective analyses of large healthcare databases concur that metformin reduces the incidence of myocardial infarction and increases survival in these patients. This apparently vasoprotective effect appears to be independent of the blood glucose-lowering efficacy. Metformin has long been known to reduce the development of atherosclerotic lesions in animal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

Metformin use in renal disease.

JPMA. The Journal of the Pakistan Medical Association • 2017

Metformin: historical overview

Diabetologia • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 99 references

Metformin--the gold standard in type 2 diabetes: what does the evidence tell us?

Diabetes, obesity & metabolism • 2009
View 4 Excerpts
Highly Influenced

Metformin: intrinsic vasculoprotective properties.

Diabetes technology & therapeutics • 2000
View 4 Excerpts
Highly Influenced

Metformin: a review of its metabolic effects

K Cusi, RA DeFronzo
Diabetes Revs • 1998
View 4 Excerpts
Highly Influenced

Oxidative stress and endothelium influenced by metformin in type 2 diabetes mellitus

J Skrha, M Praznv, J Milgertova
Eur J Clin Pharmacol • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…